Polarizing PAR Proteins

Establishment of PAR polarity domains in the one cell C. elegans embryo is triggered by the paternal centrosomes (here labeled with GFP::γ-tubulin), which contact the cell cortex. This induces segregation of PAR-6 (red) into the anterior, allowing formation of a posterior PAR-2 domain (cyan). DNA is labeled in red.

© Goehring Lab 2014