Polarizing PAR Proteins

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Establishment of PAR polarity domains in the one cell C. elegans embryo is triggered by the paternal centrosomes (here labeled with GFP::γ-tubulin), which contact the cell cortex. This induces segregation of PAR-6 (red) into the anterior, allowing formation of a posterior PAR-2 domain (green). DNA is labeled in red.  Download


© Goehring Lab 2014